Background:  The rapid and accurate diagnosis of cardiac syncope in patients presenting with syncope to the emergency department is  an important unmet clinical need.  The aim of the BASEL IX (BAsel Syncope EvaLuation Study) Trial is to evaluate the diagnostic accuracy of elements of the patient history, elements of the physical examination, clinical judgment, digital 12-lead ECG and novel cardiovascular  biomarkers in the diagnosis and risk stratification of patients with syncope. Trial Registration No: NCT 01548352 (   Link  Trial Status: Enrollment active  Enrolling Centers:  Switzerland Worldwide: University Hospital Basel Active Centers: Cantonal Hospital Liestal Spain: Hospital Clinico San Carlos, Madrid Hospital Lachen Hospital Clinic de Barcelona University Hospital Zürich USA: Baylor College of Medicine, Houston Australia: Royal Brisb. a. Women’s Hosp., Brisbane New Zealand: Canterbury District Health Board, Christchurch Poland: Medical University of Silesia, Zabrze Inactive Centers (recuitment completed) Spain: Hospital del mar, Barcelona Germany: Klinikum Nürnberg Italy: Azienda Ospedaliera Sant Andrea, Rome Core Study Team: 
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