Background:  The rapid and accurate diagnosis of cardiac syncope in patients presenting with syncope to the emergency department is  an important unmet clinical need.  The aim of the BASEL IX (BAsel Syncope EvaLuation Study) Trial is to evaluate the diagnostic accuracy of elements of the patient history, elements of the physical examination, clinical judgment, digital 12-lead ECG and novel cardiovascular  biomarkers in the diagnosis and risk stratification of patients with syncope. Trial Registration No: NCT 01548352 (   Link  Trial Status: Enrollment active  Enrolling Centers:  Worldwide: Recruiting: Recuitment completed: Spain: Hospital Clinico San Carlos, Madrid Australia: Royal Brisbane a. Women’s Hosp., Hospital Clinic Universitari, Barcelona USA: Baylor College of Medicine, Houston USA: Baylor College of Medicine, Houston Spain: Hospital del Mar, Barcelona New Zealand: Christchurch Public Hospital Germany: Klinikum Nürnberg Argentina: Instituto Cardiovascular Italy: Sant'Andrea Hospital, Rome de Buenos Aires Switzerland: Spital Lachen Poland: Szpitala Specjalistycznego w Zabrzu University Hospital Basel India: Medanta The Medicity, Haryana Switzerland: Kantonsspital Liestal, Luzern Kantonsspital University Hospital Zürich Core Study Team: 
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