C. Stelzig, MSc
Background:  The aim of APACE (Advantageous Predictors of Acute Coronary Syndrome Evaluation Study) is to test if the use of  meticulous patient history, digital and analogue ECG parameter and novel biomarkers (including novel, sensitive and  high-sensitive cardiac troponin I and T, Copeptin, myeloperoxydase, Endothelin) can provide a faster detection or  exclusion of acute myocardial infarction in patients presenting with acute chest pain to the emergency department. Introduction Video:       (1:21 Min)  Trial Registration No: NCT00470587 (clinicaltrials.gov)    Link  Trial Status: Enrollment active (n>3500 patients), ongoing data analysis and publishing  Enrolling Centers:  Switzerland Worldwide: Cantonal Hospital Liestal Czech Republic: Brno  University Hospital Basel  Poland: Zabrze University Hospital Zürich  Spain: Hospital Clinico San Carlos, Madrid  Hospital Clinic, Barcelona  Core Study Team:  Important Publications: (click on links to see abstracts) 
Home News Team Current Studies Publications Events Cooperations Contact
© Christian Mueller, 2012 - 2017  │  Disclaimer  │  Imprint  │  Webmaster │ Last Update: August 2017
Dr. P. Haaf Dr. T. Reichlin Dr. Karin Wildi
APACE
Incremental value of copeptin for rapid rule out of acute myocardial infarction.Reichlin T, Hochholzer W, Stelzig C et al. J Am Coll Cardiol. 2009 Jun 30;54(1):60-8. Incremental value of high-sensitivity cardiac troponin T for risk prediction in patients with suspected acute myocardial infarction.Hochholzer W, Reichlin T, Twerenbold R et al. Clin Chem. 2011 Sep;57(9):1318-26. Early diagnosis of acute myocardial infarction in patients with pre-existing coronary artery disease using more sensitive cardiac troponin assays.Reiter M, Twerenbold R, Reichlin T et al. Eur Heart J. 2011 Oct 31. Early diagnosis of acute myocardial infarction in the elderly using more sensitive cardiac troponin assays.Reiter M, Twerenbold R, Reichlin T et al. Eur Heart J. 2011 Jun;32(11):1379-89. Utility of absolute and relative changes in cardiac troponin concentrations in the early diagnosis of acute myocardial infarction.Reichlin T, Irfan A, Twerenbold R et al. Circulation. 2011 Jul 12;124(2):136-45. Early diagnosis of myocardial infarction with sensitive cardiac troponin assays.Reichlin T, Hochholzer W, Bassetti S et al. N Engl J Med. 2009 Aug 27;361(9):858-67.
APACE
Dr. M. Rubini Giménez Dominik Breitenbücher Christine Kruse Markus Riesterer Dr. R. Twerenbold MAPS MAPS Devran Topyürek Julian Pfäffli Michael Tschuck Patrick Bergsma