Name: Christian Eugen Mueller Date of Birth: April 24th, 1968 Marital Status: Married, two childen (15 & 13 years) Nationality: Swiss & German Academic Status: Professor, Chefarzt Position: Director Cardiovascular Research Institute Basel Address: Department of Cardiology, University Hospital Basel Petersgraben 4, 4031 Basel, Tel: 0041 61328 65 49 christian.mueller@usb.ch Website: www.dyspnea.ch

Publications: Author and co-author of >820 written peer review including 492 original publications (274 as first or last author) Education, Training, and Academic Career 1995 MD, Faculty of Medicine, University Munich 1993-1996 Thesis 1995-1999 Herz-Zentrum Bad Krozingen, Germany 1995-1996 Postdoctoral Research Fellowship in Intravascular Ultrasound (Prof. John McB. Hodgson, Case Western University, Cleveland, USA) 1999-now University Hospital Basel, Dep. of Internal Medicine / Intensive Care / Anesthesia / Cardiology 2002 Board Certification in Internal Medicine, FMH 2003 Board Certification in Intensive Care Medicine, FMH 2003 Board Certification in Cardiology, FMH 2003 Habilitation and Venia docendi, Faculty of Medicine, University Basel 2004 Professorship Swiss National Science Foundation 2005 Fellow of the European Society of Cardiology 2007 Associate professur, Faculty of Medicine, University Basel 2011-now Full Professor of Cardiology, Faculty of Medicine, University Basel Institutional Tasks - Training and supervision of graduate and postgraduate students in clinical research & cardiology - Support and supervision of different cardiovascular research groups - Conduct of high-quality clinical research with immediate impact on patient care - Obtaining competitive funding for the CRIB and for own research - Inpatient services cardiology department & treatment standards cardiology - Leitung Universitäres Herzzentrum & CRIB, Personalkommission Kardiologie - Treatment standards acute cardiology - Participation in different committees of the Medical Faculty, including chairing some Previous support of the Swiss National Science Foundation 2001-2003 BASEL study 2004-2010 Integration of B-type natriuretic peptide into clinical practice 2011-2015 APACE 2012-2016 BASEL IX 2015-2018 APACE Validation 2018-2020 Swiss-PMI Supervision of young Researchers (since 2001, current titles are listed, names provided for those with at least one first authorship in a peer-reviewed publication) Prof. Dr. M. Christ, Prof. Dr. D. Staub, Prof. Dr. T. Reichlin, Prof Dr. T. Breidthardt, Prof. Dr. W. Hochholzer, Prof. Dr. R. Twerenbold, Dr. M. Reiter, Dr. K. Wildi, K. Laule, Dr. C. Zellweger, Dr. N. Schaub, PD Dr. P. Haaf, Dr. J. Meissner, Dr. M. Noveanu, Dr. M. Potocki, Dr. B. Moehring, Dr. A. Irfan, Dr. M. Rubini Gimenez, Dr. R. Hoeller, Dr. M. Müller, Dr. B. Meller, Dr. S. Zürcher, Dr. C. Balmelli, Dr. G. Lee, Dr. S. Mann Sou, Dr. Y. Tanglay, Dr. Z. Moreno Weidmann, Dr. F. Stallone, Dr. P. Hillinger, Dr. J. Boeddinghaus, Dr. T. Nestelberger, Dr. Ch. Puelacher, Dr. P. Badertscher, Dr. D. Flores, Dr. H. Singeisen, Dr. J. du Faye de Lavallaz, U. Honegger, Dr. Z. Sabti, Dr. N. Kozhuharov, Dr. D. Mueller, Dr. L. Sazgary, Dr. P. Lopez Ayala, Dr. D. Wussler, Dr. J. Walter, Dr. L. Koechlin, Dr. T. Zimmermann, Dr. B. Hafner, Dr. A. Prepoudis, Dr. A. Yufera Sanchez, Dr. S. Frey, Dr. H. Schoepfer, Dr. M. Belkin, Dr. T. Coscia, Dr. R. Meister, Dr. M. Liffert, Dr. M. Amrein, Dr. K. Arslani, Dr. R. Giger, Dr. V. Troester, Dr. P. Ratmann, Dr. A. Prepoudis, Dr. V. Widmer, Dr. E. Michou, Dr. J. Gueckel, Dr. P. Muzyk, Dr. T. Resa, Dr. D. Mueller, plus 110 MD doctoral students (with monography dissertation) and 55 master students. The following Professors have done their sabbatical in my research team: Prof. A. Mebazaa, Prof. C. Meune, Prof. D. Gualandro, Prof. O. Miro Teaching activities - Research tutorials and direct supervision and training for doctoral students (13 per year) and master students (7 per year) - Courses/lectures in cardiology (about 50 per year) - Bedside teaching to junior physicians Panels, Boards, expert activities 2004- Swiss Society of Cardiology, Swiss Society of Intensive Care Medicine, Swiss Society of Internal Medicine, Member 2010-2016 European Society of Cardiology (ESC), Acute Cardiovascular Care Association, Board member 2016-2020 ESC, Heart Failure Association, Board Member 2008- ESC, Biomarker Study group, Member, since 2021 chair 2014- ESC-ACVC, Acute Heart Failure Study group, founder & chair, now member 2016- ESC, HFA, Committee for Diagnosis, chair, now member 2014-2020 ESC, HFA, Committee for Acute Heart Failure, member 2013-2015 ESC, Section Coordinator for 2015 NSTACS-Guideline 2010- ESC, Reviewer for several other Practice Guidelines 2008- GREAT-network: Co-founder & Vice-President 2018-2020 ESC, Section Coordinator for 2020 NSTACS-Guideline 2018-2022 ESC, Clinical Practice Guideline Committee Associate Editor European Heart Journal 2016-2020, EHJ -ACVC 2020 - , SMW 2020 Editorial Board Journal of the American College of Cardiology, Heart, LO Innere Medizin Reviewer for New England Journal of Medicine, Lancet, Nature, JAMA, Circulation, JACC, EHJ, Nature Reviews Cardiol, Am J RCCM, JAMA Internal Medicine, BMJ,…SNF, DHF, NHF, … Overall, >150 scientific reviews per year, Advisory boards of several biomedical companies Organisation of Scientific Meetings Scientific committee ESC-ACVC 2014 Geneva, plus several other meetings; Chair scientific committee International GREAT Meeting 2010-2021; Awards, Fellowships: Investigator Award Intensive Care 2001+2003+2005, Swiss Society of Internal Medicine 2004, Viollier 2004, Swiss Heart Foundation 2005, Theodor Naegeli Award 2007, Magda Heras Award of the ESC-ACCA 2014; Academic Rankings: 2017 Top 3, University of Zürich, Chair of cardiology Clarivate Web of Science 2019: Among Top 1% most cited researchers in clinical medicine worldwide, among Top 3 in Switzerland Scientific achievements: 1) Scientific publications: Author and co-author of >820 written peer-review publications including 492 original publications (274 as first or last author) 2) Knowledge transfer, specific contribution: Oral contributions to international conferences: Regular speaker at international conferences with 15-20 oral presentation per year, last 5 years: Annual meetings of the European Society of Cardiology 2016-2021 Heart Failure Association 2016-2021, ESC ACVC 2016-2021, GREAT 2016-2021 Integrated Management of Cardiovascular Disease 2016-2021 Outreach activities aimed at clinicians and medical personnel Scientific committee MedArt Basel 2012-2021; chair Cardio Update Basel 2012-2021, webinars of “ESC TV”, ESC- ACVC webinars, Co-Founder of ESC ACVC Biomarker Talks, CRIB-Today videos featuring young researchers and their latest publications; Educational and Implementation efforts related to Clinical Practice Guidelines of the ESC, including first authorship and co-authorships of specific educational Q&A documents accompanying the 2015 and 2020 ESC NSTE-ACS guidelines, as well as co-author and reviewer activities of several other Clinical Practice Guidelines of the ESC. Leading interdisciplinary educational and implementation efforts of the SGK, the Swiss Society of Laboratory Medicine, and the diagnostic industry in Switzerland related to standardization and harmonization of the reporting of cardiac troponin concentrations to avoid medical harm to patients by erroneous interpretation of results. Editorials in medical newspapers targeting primary care physicians with topics related to major scientific advances and their possible clinical implications. Chair and Member of several study groups within the ESC coordinating and producing outreach activities (educational position papers, webinars, symposia) related to specific cardiac disorders. Faculty Postgraduate Course for Heart Failure (Zürich & London).